Protocol for Using Beta-1, 3-D glucan
in Dental Surgery
By John L. Tate, D.D.S.
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1. A therapeutic dose is required for both elective and emergency surgery. A five-day treatment is considered a minimum.*

2. Determine therapeutic dosage: 25 mg per kilogram of body weight. (Kilogram=2.2 lbs.)

Example: Calculating the therapeutic dose for a 150 lb. Person:

150 lbs. divided by 2.2 = 68 Kilograms x 25 mg=1700 mg daily. This is the therapeutic dosage for maximum macrophage activity.

An alternate approximate calculation is 500 mg of Beta-1, 3-D glucan per 50 lbs. of body weight.

3. Elective Surgery:

Use calculated therapeutic dose for 5 days (2 days before surgery, the day of, and 2 days after surgery).

Emergency Surgery:

Use calculated therapeutic dose for 5 days beginning the day of surgery.

4. To maximize uptake of Beta-1, 3-D glucan it should always be taken on an empty stomach. Wait at least 30 minutes before eating anything. An ample amount of pure water should be used to swallow the material.

5. An appropriate diet and food supplements will support the immune response in this healing crisis. This usually involves raw vegetable juices and body detoxification procedures designed for metabolic individuality. A healthy alkalinity promotes the immune response.

6. A follow up maintenance or preventative dosage is of 100-500 mg daily of Beta-1, 3-D glucan is recommended.

7. Cost: The average patient will require a 5-day course of fifteen 500 mg. capsules which will cost the patient approximately $20.00. Professional and volume discounts are available. Contact Transfer Point at their toll free number for details 1-877-464-6304.

*Beta-1, 3-D glucan should be used in addition to the usual legally required antibiotic prescription. For those who are allergic to the penicillin forms, I have used Beta-1, 3-D glucan alone with excellent healing and no dry sockets. Significant peer reviewed literature using Beta Glucan as an adjunct to standard antibiotic protocols produced significantly better results than antibiotics used alone.^1,2,3,4,5 There have been 6 (six) cases in my practice when patients with multiple chemical sensitivities and allergies to "all antibiotics" chose to use Beta-1, 3-D glucan alone in difficult surgical cases. The clinical results were successful and without complication. The 6 (six) cases were comprised of cavitations and failed root canals. A supporting physician was in attendance.

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References:

1. Newspaper quote Spartanburg Herald Journal (9-13-99) "It's potentially an extremely serious problem." Said Dr. Mitchel Cohen of the Centers for Disease Control (CDC) of Atlanta, Ga. "Any new drugs that might be developed to cope with the deadly bacteria are at least five to seven years away, and drug companies are not pursuing them eagerly", Cohen said.

2. Prophylaxis with the immunomodulator PGG glucan enhances antibiotic efficiency in rats infected with antibiotic-resistant bacteria. Tzianabos AO, Cisneros R.I. Channing Laboratory Brigham and Women 's Hospital, Harvard Medical School, Boston, MA 02113, USA, Ann NY Acad. Sci., 1996, Oct. 25, 797:285-7

3. Browder W., et. al.; Beneficial effect of enhanced macrophage function in the trauma patient. (Ann Surg, 1990 May, Abstract available) [MedLine]

4. Babineau TJ, et. al.; A phase II multicenter, double blind, randomized, placebo-controlled study of three dosages of an immunomodulator (PGG-glucan) in high-risk surgical patients [see comments] (Arch Surg., 1994 Nov., Abstract available) [MedLine]

5. "Glucan-based macrophage stimulation may prevent infections in trauma and surgical patients." Repeated from Drug & Therapy Perspectives, 1996, Aug. 19; 8(4): 6-7

John L. Tate, DDS
2088 East Main St.
Spartanburg, SC 29307
Telephone: 864-582-4441 • Fax: 864-582-4489
Email: johnltatedds@aol.com